血糖稍高亦增加心脏病风险
2012-06-16 23:33:33 来源: 丁香园 作者: 评论:0 点击:
Even Slight Blood Glucose Increases Raise Heart Disease Risk
血糖稍高亦增加心脏病风险
Individuals, including non-diabetics, are 69% more likely to develop ischemic cardiovascular disease if glucose levels in their blood are slightly elevated, say researchers.
研究人员说,如果个体血糖水平轻微增高(包括非糖尿病者),那么他发生缺血性心血管疾病的可能性将增加69%。
The study, which involves more than 80,000 people, was conducted by researchers at the University of Copenhagen and is published in the Journal of the American College of Cardiology. Until now, the leading threat to global heart health had been cholesterol.
这一包含了8000多人的研究由哥本哈根大学的研究人员领导,并且发表在美国心脏病学会杂志。直至目前,威胁心脏健康的首要因素一直是胆固醇。
Marianne Benn, chief physician at Copenhagen University Hospital and associate professor at the University of Copenhagen, explained:
哥本哈根大学医院主任医师、哥本哈根大学助理教授Marianne Benn,解释道:
"We know that diabetics and people with high cholesterol levels are prone to ischemic heart disease, but our study also made it possible to look at blood glucose level in isolation. It is surprising that even a slightly higher blood glucose value appears to be dangerous over a longer period - and that sugar alone makes a negative difference."
“我们直到糖尿病和高胆固醇水平更易患缺血性心脏病,但我们的研究也使独立考察血糖水平的影响变为可能。即使血糖值稍高在长期看来仍然危险的结果令我们惊异。单独的糖导致的是负性差异。
Although healthy individuals without diabetes have a normal, fasting blood glucose value of less than 6 mmol (=108 mg) glucose per liter blood, the researchers found that over several years, just a slight increase (1 mmol [18mg) in blood glucose increases the risk of heart attack by 69%.
研究人员发现,即使无糖尿病的健康个体血糖正常、空腹血糖值在6mmol(=108mg)/L以下,几年之后,仅仅血糖的稍微升高(1mmol[18mg])就将突发心脏病的风险增加了69%。
The researchers examined data from The Copenhagen General Population Study, The Copenhagen City Heart Study, and The Copenhagen Ischemic Heart Disease Study, which together involved 80,522 Danes.
研究人员调查了哥本哈根总体人口学研究、哥本哈根城市心脏研究以及哥本哈根缺血性心脏病研究中共计80522名丹麦人的数据
They found that a slightly elevated level of blood sugar is enough on its own to cause cardiovascular damage.
他们发现轻微增高的血糖水平本身已足够导致心血管损害。
However, these studies are not enough to document an association between cardiovascular disease and higher blood glucose levels. According to the researchers, participants of these studies may share physical problems or characteristics that influence their weight and heart. However, in the present studies the genetic analyses used strip distracting elements from the analyses from the three large studies. With sugar getting the full focus.
然而这些研究并不足以证明心血管疾病和增高的血糖水平之间的关联。根据研究人员说法,这些研究的参与者可能都有健康问题或者对他们体重和心脏造成影响的性格因素。然而在目前的研究中应用了去除上述三个大型研究中分析干扰因素的遗传分析。糖收到了全面的关注。
Although researchers believe that the risk of ischemic cardiovascular disease is directly affected by glucose, they do not know why. They state that in order to benefit health globally, sugar intake should be limited.
虽然研究人员相信缺血性心血管疾病的风险是由糖直接导致,但他们不明所以然。他们说道,为使全球健康获益,应该限制糖的摄入。
Borge Nordestgaard, chief physician at Copenhagen University Hospital and clinical professor at the Faculty of Health and Medical Sciences, University of Copenhagen, said:
哥本哈根大学医院主任医师、哥本哈根大学卫生和医学科学系临床教授Borge Nordestgaard说道:
"The World Health Organization estimates that 6 per cent of all deaths are due to elevated blood glucose. Therefore, our results may potentially have great importance for the design of programs to prevent heart disease and early death worldwide."
“世界卫生组织估计所有死亡中的6%是由于血糖增高引起的。因此,我们得出的结果可能有在设计全球范围内心脏疾病以及早逝的预防方案中发挥重大作用的潜力。”
According to the World Health Organization, 17 million individuals die from heart-related disease each year and this figure is expected to increase in the coming years.
根据世界卫生组织的说法,每年有1700万名患者死于心脏相关疾病,并且在未来几年中这一数字将有所增加。
血糖稍高亦增加心脏病风险
Individuals, including non-diabetics, are 69% more likely to develop ischemic cardiovascular disease if glucose levels in their blood are slightly elevated, say researchers.
研究人员说,如果个体血糖水平轻微增高(包括非糖尿病者),那么他发生缺血性心血管疾病的可能性将增加69%。
The study, which involves more than 80,000 people, was conducted by researchers at the University of Copenhagen and is published in the Journal of the American College of Cardiology. Until now, the leading threat to global heart health had been cholesterol.
这一包含了8000多人的研究由哥本哈根大学的研究人员领导,并且发表在美国心脏病学会杂志。直至目前,威胁心脏健康的首要因素一直是胆固醇。
Marianne Benn, chief physician at Copenhagen University Hospital and associate professor at the University of Copenhagen, explained:
哥本哈根大学医院主任医师、哥本哈根大学助理教授Marianne Benn,解释道:
"We know that diabetics and people with high cholesterol levels are prone to ischemic heart disease, but our study also made it possible to look at blood glucose level in isolation. It is surprising that even a slightly higher blood glucose value appears to be dangerous over a longer period - and that sugar alone makes a negative difference."
“我们直到糖尿病和高胆固醇水平更易患缺血性心脏病,但我们的研究也使独立考察血糖水平的影响变为可能。即使血糖值稍高在长期看来仍然危险的结果令我们惊异。单独的糖导致的是负性差异。
Although healthy individuals without diabetes have a normal, fasting blood glucose value of less than 6 mmol (=108 mg) glucose per liter blood, the researchers found that over several years, just a slight increase (1 mmol [18mg) in blood glucose increases the risk of heart attack by 69%.
研究人员发现,即使无糖尿病的健康个体血糖正常、空腹血糖值在6mmol(=108mg)/L以下,几年之后,仅仅血糖的稍微升高(1mmol[18mg])就将突发心脏病的风险增加了69%。
The researchers examined data from The Copenhagen General Population Study, The Copenhagen City Heart Study, and The Copenhagen Ischemic Heart Disease Study, which together involved 80,522 Danes.
研究人员调查了哥本哈根总体人口学研究、哥本哈根城市心脏研究以及哥本哈根缺血性心脏病研究中共计80522名丹麦人的数据
They found that a slightly elevated level of blood sugar is enough on its own to cause cardiovascular damage.
他们发现轻微增高的血糖水平本身已足够导致心血管损害。
However, these studies are not enough to document an association between cardiovascular disease and higher blood glucose levels. According to the researchers, participants of these studies may share physical problems or characteristics that influence their weight and heart. However, in the present studies the genetic analyses used strip distracting elements from the analyses from the three large studies. With sugar getting the full focus.
然而这些研究并不足以证明心血管疾病和增高的血糖水平之间的关联。根据研究人员说法,这些研究的参与者可能都有健康问题或者对他们体重和心脏造成影响的性格因素。然而在目前的研究中应用了去除上述三个大型研究中分析干扰因素的遗传分析。糖收到了全面的关注。
Although researchers believe that the risk of ischemic cardiovascular disease is directly affected by glucose, they do not know why. They state that in order to benefit health globally, sugar intake should be limited.
虽然研究人员相信缺血性心血管疾病的风险是由糖直接导致,但他们不明所以然。他们说道,为使全球健康获益,应该限制糖的摄入。
Borge Nordestgaard, chief physician at Copenhagen University Hospital and clinical professor at the Faculty of Health and Medical Sciences, University of Copenhagen, said:
哥本哈根大学医院主任医师、哥本哈根大学卫生和医学科学系临床教授Borge Nordestgaard说道:
"The World Health Organization estimates that 6 per cent of all deaths are due to elevated blood glucose. Therefore, our results may potentially have great importance for the design of programs to prevent heart disease and early death worldwide."
“世界卫生组织估计所有死亡中的6%是由于血糖增高引起的。因此,我们得出的结果可能有在设计全球范围内心脏疾病以及早逝的预防方案中发挥重大作用的潜力。”
According to the World Health Organization, 17 million individuals die from heart-related disease each year and this figure is expected to increase in the coming years.
根据世界卫生组织的说法,每年有1700万名患者死于心脏相关疾病,并且在未来几年中这一数字将有所增加。
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